Describing the undiscovered

Resistant plus susceptible tuberculosis: the undiscovered country.

Before the emergence of molecular epidemiology techniques, the conceptual approach to tuberculosis treatment seemed straightforward. The clinical laboratory sent the patient’s isolate (singular) for testing at a reference laboratory, which would perform a drug-susceptibility test (DST) whose findings were reported as a categorical result (ie, susceptible or resistant). This information then gui...

Undiscovered Bat Hosts of Filoviruses

Ebola and other filoviruses pose significant public health and conservation threats by causing high mortality in primates, including humans. Preventing future outbreaks of ebolavirus depends on identifying wildlife reservoirs, but extraordinarily high biodiversity of potential hosts in temporally dynamic environments of equatorial Africa contributes to sporadic, unpredictable outbreaks that hav...

The Undiscovered Country: The Future of Industrial Automation

A New Origin of Sugarcane: the Undiscovered Species

The Saccharum sensu stricto (s.s) genus consists of three recognised species: S. spontaneum, S. officinarum and S. robustum, and three subspecies: S. sinense, S. barberi and S. edule. Currently, limited knowledge is available about the precise descent of these species from one another. Modern sugarcane arose through the ‘Nobilization’ process, and it is believed that S. officinarum and S. spont...

An Undiscovered “Super -ility” of Smart Healthcare

CONSIDER A COMPLEX, smart healthcare system, whether it’s an assistive or therapeutic device, record management system, diagnostic system, physicianorder-entry system, or any healthcarerelated hardware or software system. These systems aim to improve the degree of certain qualities or attributes (“-ilities”) such as availability, privacy, reliability, safety, security, and, moreover, their noni...